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Faculty Bio - Lan Kong, PhD
Assistant Professor, Biostatistics
Education BS, Biomedical Engineering, Tianjin Medical University MS, Biostatistics, University of North Carolina at Chapel Hill PhD, Biostatistics, University of North Carolina at Chapel Hill Research Interests My current research focuses on the statistical methods for evaluation of biomarker performance, joint analysis of censored longitudinal biomarker and clinical outcomes, semiparametric survival modeling and case-cohort design. I also collaborate in the CRISMA Center (Clinical Research, Investigation, and Systems Modeling of Acute illness) at the department of critical care medicine. My collaboration projects are mainly in the areas of sepsis and acute kidney injury. (Health Sciences Faculty Research Interests Project)
Lee M, Kong L. Median regression for longitudinal left-censored biomarker data subject to detection limit. Statistics in Biopharmaceutical Research 2011, 3(2):363-371. Srisawat N, Wen X, Lee M, Kong L, Elder M, Carter M, Unruh M, Finkel K, Vijayan A, Ramkumar M, Paganini E, Singbartl K, Palevsky PM, Kellum JA for the BioMaRK Investigators. Urinary biomarkers predict renal recovery in critically ill patients with renal support: result from biomark study. Clinical Journal of the American Society of Nephrology 2011. In press. Srisawat N, Murugan R, Lee M, Kong L, Carter M, Angus DC, Kellum JA for the GenIMS Investigators. Plasma neutrophil gelatinase-associated lipocalin predicts recovery from acute kidney injury following community-acquired pneumonia. Kidney International 2011. In press. Milbrandt EB, Yende S, Kellum JA, Kong L, Delude RL, Weissfeld LA, Angus DC. Understanding the potential role of statins in pneumonia and sepsis. Critical Care Medicine. Published online: 21 April 2011. PMID:21516038. Huang DT, Clermont G, Kong L, Weissfeld LA, J. Bryan Sexton, Rowan KM, Angus DC. Intensive care unit safety culture and outcomes: a U.S. multicenter study. International Journal for Quality in Health Care 2010, 22(3):151–161. Murugan R, Karajala-Subramanyam V, Lee M, Yende S, Kong L, Carter M, Angus DC, Kellum JA. Acute kidney injury in non-severe pneumonia is associated with an increased immune response and lower survival. Kidney International 2010, 77:527-535. Kong L, Cai J. Case-cohort analysis with accelerated failure time model. Biometrics 2009, 65:135-142. Michael RC, Yende S, D'Angelo G, Kong L, Kellum JA, Milbrandt EB, Dooley C, Mayr FB, Barnato AE, Weissfeld L, Angus DC. Differences in immune response may explain lower survival among older men with pneumonia. Critical Care Medicine 2009, 37(5):1655-62. Watson RS, Clermont G, Kinsella JP, Kong L, Arendt RE, Cutter G, Linde-Zwirble WT, Abman SH, Angus DC on behalf of the Prolonged Outcomes after Nitric Oxide (PrONOx) Investigators. Clinical and economic effects at one year of corrected age after a randomized trial of inhaled nitric oxide in premature newborns with respiratory failure. Pediatrics 2009, 124(5):1333-1343. Yende S, Angus DC, Kong L, Kellum JA, Weissfeld LA, Ferrell R, Finegold D, Carter M, Leng L, Peng Z, Bucala R. The influence of macrophage migration inhibitory factor gene polymorphisms on outcome from community-acquired pneumonia. The FASEB Journal 2009, 23(8):2403-11. Kellum JA, Kong L, Fink MP, Weissfeld LA, Yealy DM, Pinsky MR, Fine J, Krichevsky A, Delude RL, Angus DC, for the GenIMS Investigators. Understanding the inflammatory cytokine response in pneumonia and sepsis: Results of the GenIMS study. Archives of Internal Medicine 2007, 167(15):1655-1663. Kong L, Cai J, Sen PK. Asymptotic results for fitting semiparametric transformation models to failure time data from a case-cohort design. Statistica Sinica 2006, 16(1):135-151. Kong L, Kohberger RC, Koch GG. Design of vaccine equivalence/non-inferiority trials with correlated multiple binomial endpoints. Journal of Biopharmaceutical Statistics 2006, 16(4):555-572. Kong L, Koch GG, Liu T, Wang H. Performance of some multiple testing procedures to compare three doses of a test drug and placebo. Pharmaceutical Statistics 2005, 4(1):25-35. Kong L, Milbrandt EB, Weissfeld LA. Advances in statistical methodology and their application in critical care. Current Opinion in Critical Care 2004, 10(5):391-394. Kong L, Cai J, Sen PK. Weighted estimating equations for semiparametric transformation models with censored data from a case-cohort design. Biometrika 2004, 91(2):305-319. Kong L, Kohberger RC, Koch GG. Type I error and power in non-inferiority/equivalence trials with correlated multiple endpoints: an example from vaccine development trials. Journal of Biopharmaceutical Statistics 2004, 14(4):893-907. Contact Information 313 Parran Hall 130 DeSoto Street Pittsburgh, PA 15261 Telephone: 412-624-3638 Facsimile: 412-624-2183 Email: lkong@pitt.edu Last reviewed: June 16, 2011
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