Professor, Biostatistics

• Education
• Research Interests
• Selected Publications
• Contact Information

Education

M.A., University of Pittsburgh
Ph.D., University of Pittsburgh

Research Interests

My primary research interests are currently focused in the areas of biomarker and neuroimaging data. I am currently working on statistical methods to analyze biomarker data that is truncated due to the sensitivity of the assay for measuring the biomarker. I have been working on the development of statistical methods where either the outcome or covariate in a given model is subject to left censoring.

I also work in the area of imaging with a focus on neuroimaging. I am working on the development of methods that will enhance the implementation of dimension reduction methods for the analysis of neuroimaging data. I am also working on the development of decision rules for detection of disease in an image. (Health Sciences Faculty Research Interests Project)

Selected Publications

Sattar A, Weissfeld LA, Molenberghs G. Analysis of non-ignorable missing and left-censored longitudinal data using weighted random effects tobit model. Statistics in Medicine 2011, 30(27): 3167-80, 2011. PMID: 21898524.

Lee MJ, Kong L, Weissfeld, L. Multiple Imputation for left-censored biomarker data based on Gibbs Sampling method. Statistics in Medicine Feb 22, 2012. PMID: 22359320.

Rosario BL, Weissfeld LA, Laymon CM, Mathis CA, Klunk WE, Bergine MD, James JA, Hoge JA, Price JC.  Inter-rater reliability of manual and automated region-of-interest delineation for PiB PET. Neuroimage 2011, 55(3): 933-41.

Sattar A, Weissfeld LA, Molenberghs G.  Analysis of non-ignorable missing and left-censored longitudinal data using weighted random effects tobit model.  To appear in Statistics in Medicine, 2011.

Shen C, Weissfeld L.  A copula model for repeated measurements with non-ignorable non-monotone missing outcome”.  Statistics in Medicine 2006, 25(14): 2427-2440.

D’Angelo G, Weissfeld L.  Covariates missing by design:  comparison of the efficient score to other weighted methods. Statistics in Medicine 2006, 26(10): 2137-2153.

D’Angelo G, Weissfeld L.  An index approach to the Cox model with left censored covariates.  Statistics in Medicine 2008, 27(22): 4502-4514.

Rosario BL, Ziolko SK, Weissfeld LA, Price JC.  Assessment of parameter settings for SPM5 spatial normalization of structural MRI data:  application to type 2 diabetes.  Neuroimage  2008, 41(2): 363-70.

Qin L, Weissfeld L, Shen C, Levine, M.  A two-latent-class model for smoking cessation with informative dropouts.  Communications in Statistics – Theory and Methods 2009, 38(15): 2604-2619.

Contact Information

305 Parran Hall
130 DeSoto Street
Pittsburgh, PA 15261
Telephone: 412-624-3023
Facsimile: 412-624-2183
Email: lweis@pitt.edu

Last reviewed: June 21, 2012