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John J. Grefenstette, PhD
Visiting Professor, Biostatistics
Director, Public Health Dynamics Laboratory
Education Ph.D., University of Pittsburgh, 1980
M.S, University of Pittsburgh, 1978
B.S., Carnegie Mellon University, 1975
Research Interests
Modeling and simulation of infectious diseases, bioinformatics,
biological network analysis, machine learning, and high-performance
computing applications to public health.
Selected Publications
"On comparing neuronal morphologies with the constrained
tree-edit-distance." Gillette TA, Grefenstette JJ. Neuroinformatics 7(3):191-4, 2009. PMID: 19636974.
"High-resolution haplotype block structure in the cattle genome."
Villa-Angulo R, Matukumalli LK, Gill CA, Choi J, Van Tassell CP,
Grefenstette JJ. BMC Genetics 10:19, 2009. PMID: 19393054; PMCID:
PMC2684545.
"Genome-wide survey of SNP variation uncovers the genetic structure of
cattle breeds." Bovine HapMap Consortium, Gibbs RA, Taylor JF, et al.
Science 324(5926):528-32, 2009 Apr 24. PMID: 19390050.
"Modeling gene regulatory networks with delayed stochastic dynamics."
Ribeiro AS, Grefenstette JJ, Kauffman SA. In Computational Methodologies
in Gene Regulatory Networks, S. Das, D. Caragea, W. H. Hsu, and
S. M. Welch (Eds.), IGI Global Publishing, 2009.
"An analysis of the class of gene regulatory functions implied by a
biochemical model." Grefenstette J, Kim S, and Kauffman S. Biosystems 84:81-90, 2006. PMID: 16384633.
"Application of machine learning in SNP discovery." Matukumalli LK,
Grefenstette JJ, Hyten DL, Choi IY, Cregan PB, Van Tassell CP. BMC Bioinformatics 7:4, 2006. PMCID: PMC1955739.
"SNP-PHAGE: High throughput SNP discovery pipeline." Matukumalli LK,
Grefenstette JJ, Hyten DL, Choi IY, Cregan PB, Van Tassell CP. BMC
Bioinformatics. 7:468, 2006. PMID: 17059604; PMCID: PMC1626092.
Contact Information
702A Parran Hall
130 DeSoto Street
Pittsburgh, PA 15261
Telephone: 412-648-9920
Email: gref@pitt.edu |
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