| | Doug Potter, PhD
Research Associate Professor, Biostatistics Education BS, Massachusetts Institute of Technology, 1967 MS, Massachusetts Institute of Technology, 1969 MS, University of Pittsburgh,1998 PhD, Massachusetts Institute of Technology, 1972 Research Interests
Statistical methodology for design and analysis of preclinical studies and early phase clinical trials in cancer; development and use of novel exact and approximate permutation tests; analysis of small datasets. Selected Publications
Ramanathan RK, Egorin MJ, Takimoto CH, Remick SC, Doroshow JH, LoRusso PA, Mulkerin DL, Grem JL, Hamilton A, Murgo AJ, Potter DM, Belani CP, Hayes MJ, Peng B, Ivy SP; National Cancer Institute Organ Dysfunction Working Group. Phase I and pharmacokinetic study of imatinib mesylate in patients with advanced malignancies and varying degrees of liver dysfunction: a study by the National Cancer Institute Organ Dysfunction Working Group. Journal of Clinical Oncology. 2008. 26(4):563-9.
Singh SV, Powolny AA, Stan SD, Xiao D, Arlotti JA, Warin R, Hahm ER, Marynowski SW, Bommareddy A, Potter DM, Dhir R. Garlic constituent diallyl trisulfide prevents development of poorly differentiated prostate cancer and pulmonary metastasis multiplicity in TRAMP mice. Cancer Research. 2008 68(22):9503-11.
Potter DM, Robust two-stage model-guided designs for phase I clinical studies (chapter). Wiley Encyclopedia of Clinical Trials. New York, John Wiley & Sons, Inc, 2007.
Potter DM. Phase I studies of chemotherapeutic agents in cancer patients: a review of the designs. Journal of Biopharmaceutical Statistics, 2006. 16:579-604.
Potter, DM. Omnibus Permutation Tests of the Association of an Ensemble of Genetic Markers with Disease in Case-Control Studies. Genetic Epidemiology, 30(5):438-46, 2006.
Potter DM, Griffiths DJ, Omnibus permutation tests of the overall null hypothesis in datasets with many covariates. Journal of Biopharmaceutical Statistics, 16(3):327-341, 2006. Potter DM. A permutation test for inference in logistic regression with small- and moderate-sized datasets. Statistics in Medicine, 24:693-708, 2005. Potter, DM. Adaptive Dose Finding for Phase I Clinical Trials of Drugs Used for Chemotherapy of Cancer. Statistics in Medicine, 21:1805-1823 2002.
Ramanathan, RK, Potter DM, Jacobs SA, Belani CP, Lim F, Kim H, Savona S, Evans T, Buchbarker D, Simon MB, Depee J, Wilson S, Gravenstein S, Trump DL. A randomized trial of influenza vaccine with GM-CSF or placebo in cancer patients. Journal of Clinical Oncology, 21:4313-4318 2002.
Contact Information One Sterling Plaza, Suite 325 201 North Craig Street Pittsburgh, PA 15213 Telephone: 412-383-1580 Facsimile: 412- 383-1535
Email: dmp71@pitt.edu |
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