| | Carol K. Redmond, ScD
Distinguished Service Professor of Public Health
Education MS(Hyg), ScD(Hyg), University of Pittsburgh Research Interests From 1967 to present Dr. Redmond has directed a series of industry-wide epidemiological studies of health risks in occupational settings. These studies, which are multi disciplinary efforts, have involved clinical specialists, industrial hygienists, biochemists, and toxicologists, in addition to biostatisticians and epidemiologist. Most notable is the study of the long-term mortality experience of almost 70,000 steelworkers which provided the primary epidemiologic data used by the Occupational Safety and Health Administration to set the standard for exposure to coke oven emissions. These studies provided valuable databases used to develop and refine statistical methodologies for quantitative risk assessment by Dr. Redmond, faculty collaborators, and graduate students in the Department of Biostatistics.
In 1972 Dr. Redmond began a collaboration with Dr. Bernard Fisher, Professor in the Department of Surgery at the University of Pittsburgh and Group Chairman for the National Surgical Adjuvant Project for Breast and Bowel Cancers (NSABP). The NSABP, an NCI funded Cooperative Cancer Clinical Trial Group, has conducted landmark randomized trials that have led to major advances in the treatment of early stage breast cancer. In 1977 she founded the NSABP Biostatistical Center which she directed until 1994. As Director of the Biostatistical Center, Dr. Redmond administered a staff of approximately 60 who participated in the design, conduct, analysis, and interpretation of numerous large multi center breast cancer treatment clinical trials. Of note are Protocol B-06, the trial that established lumpectomy plus radiation as an appropriate treatment for early stage breast cancer, and Protocol B-14, the largest double-blind trial conducted in breast cancer treatment, which provided important data on benefits and risks of long-term treatment with tamoxifen in women with Stage I receptor positive breast cancer. The collaboration included design and conduct of major multi center trials of early stage colorectal cancer treatment trials as well. She coordinated the team of statistical faculty who designed and implemented the recently completed Breast Cancer Prevention Trial (BCPT), which evaluated tamoxifen versus placebo in more than 13,000 women at increased risk for invasive breast cancer.
From 1990 to 1995 she was Co-Principal Investigator on an Agency for Health Care Policy and Research (AHCPR) grant for a Primary Outcomes Research Team (PORT) project at the University of Pittsburgh. The PORT project involved a broadly based interdisciplinary group of investigators interested in assessing the variation in outcomes of patients with community acquired pneumonia (CAP).
Dr. Redmond has a major interest in minority health research. She has participated in publications on black-white differentials in cancer patient survival. From 1985 until 1995 she was a member of the NCI Scientific Advisory Committee for the population-based social epidemiologic study of black/white differences in cancer patient survival experience and has conducted in-depth evaluation of treatment results by race within the NSABP clinical trials. In 1993 she served on the Task Force on Recruitment and Retention of Women and Minorities in Clinical Research for the Office of Research on Women's Health. (Health Sciences Faculty Research Interests Project) Courses BIOST 2090: Special Topics 3 - Clinical Trials: Methods and Practice Selected Publications "Biostatistics in Clinical Trials," edited by Redmond CK and Colton T. New Work: John Wiley & Sons, Inc., 2001. "Some Advice for Advisors." Bowman D, Bush A, Cowart D, Price D, Redmond C, Ryan L, Stone-Chestnut J, and Young B. Stats, 30: 8-10, 2001. "Validation Studies of Invasive and Total Breast Cancer Incidence." Costantino JP, Gail MH, Pee D, Anderson SJ, Redmond CK, et. al.. J. Natl Cancer Inst 91(18): 1541-8, 1999. "Issues and Findings in the Evaluation and Occupational Risk in Women." Arena VC, Costantino JP, Sussman NB, and Redmond CK. American Journal of Industrial Medicine. 36: 114-121, 1999. "Using Alternative Comparison Populations to Assess Occupational Related Mortality Risk: Results for High Nickel Alloys Workers Cohort." Arena VC, Sussman NB, Redmond CK, Costantino JP, and Trauth JM. Journal of Occupational and Environmental Medicine 40:907-916, 1998. "Parallel Line Assay," "Radioimmunoassay," and "Slope Ratio Assay." Redmond CK. Encyclopedia of Biostatistics. Armitage P and Colton T, eds. John Wiley & Sons, New York, NY, 1998. "Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study." Fisher B, Costantino JP, Wickerham DL, Redmond CK, Kavanah M, Cronin WM, Vogel V, Robidoux A, Dimitrov N, Atkins J, Daly M, Wieand S, Tan-Chiu E, Ford L and Wolmark N. Journal of the National Cancer Institute 190(18):1371-88, 1998. "Long-term tamoxifen citrate use and potential ocular toxicity." Gorin MB, Day R, Costantino JP, Fisher B, REDMOND CK, et al. American Journal of Ophthalmology, 125(4):493-501, 1998. "Prognosis among black women and white women with node-negative breast cancer: findings from two randomized clinical trials of the national surgical adjuvant breast and bowel project (NSABP)." Dignam JJ, Redmond CK, Fisher B, Costantino JP, Edwards BK. Cancer 80(1): 80-90, 1997. "Assessing Individual Risk for Breast Cancer: Risky Business." McTiernan A, Gilligan MA, Redmond C. Journal of Clinical Epidemiology, 50(5): 547-556, 1997. Contact Information 318A Parran Hall
130 DeSoto Street
Pittsburgh, PA 15261
Telephone: 412-624-1319
Facsimile: 412-624-2183
Email: ckr3@pitt.edu |  |
